Bladder & kidney health
Bladder & kidney supplements include products containing cranberry, Chanca Piedra, D-mannose and botanical Water Out formulas. The range includes NOW Foods, Swanson, OstroVit, AllNutrition and other brands. Compare ingredients, serving amounts and manufacturer directions, particularly if you take medicines or use several supplements at the same time.
25 products
Updated: 25 August 2026.
Bladder and kidney supplements: what does the category include?
The category brings together botanical extracts and other ingredients commonly found in urinary-system-related products, including cranberry, D-mannose, Water Out and Hydro Out botanical formulas, Chanca Piedra, Fo-Ti, pumpkin seed extract and other plants.
These products are not medicines for treating urinary tract infections, kidney stones or other medical conditions. Pain or burning when urinating, blood in the urine, fever, severe flank pain or suspected kidney stones should be assessed by a doctor.
At a glance
- Cranberry and D-mannose are popular ingredients in this category but do not replace treatment for an infection.
- Water Out and Hydro Out are names used for different botanical combination formulas whose ingredients vary between manufacturers.
- Chanca Piedra and Fo-Ti are traditional botanical ingredients but should not be considered substitutes for medical treatment.
- Botanical diuretic formulas may affect fluid and electrolyte balance and may interact with medicines.
Cranberry and D-mannose
Cranberry is available as an extract, powder and in combination products. D-mannose is a naturally occurring simple sugar also used in food supplements in this category.
Cranberry and D-mannose should not be marketed as treatments or guaranteed prevention for urinary tract infections. Once infection symptoms are present, supplements should not replace medical diagnosis or prescribed treatment.
Water Out and Hydro Out
The range may contain several botanical combination formulas with a similar concept:
- Water Out (NOW Foods) - a multi-ingredient botanical formula.
- Water Out (AllNutrition) - a formula with its own blend of botanical ingredients.
- Hydro Out Diuretic (OstroVit) - another multi-ingredient botanical product.
Formulas can differ considerably between brands. Compare the specific extracts, amounts per serving, recommended daily serving and manufacturer warnings rather than relying only on the product name.
Chanca Piedra
Chanca Piedra (Phyllanthus niruri) is a plant with a history of traditional use in South America. It is sometimes known as “stone breaker” because of its historical association with the urinary system.
If kidney stones have been diagnosed or are suspected, Chanca Piedra should not be used as a replacement for medical assessment and treatment.
Fo-Ti
Fo-Ti (Polygonum multiflorum) is a plant used in traditional Chinese practice. Cases of liver injury have been reported in association with Polygonum multiflorum products, so directions and contraindications require particular attention.
If unusual symptoms occur, including yellowing of the skin or eyes, dark urine, nausea or pronounced weakness, stop using the product and seek medical advice.
Pumpkin seed extract and other botanicals
The category may also contain water-soluble pumpkin seed extract, watercress, Galium aparine, goji, jujube and other botanical ingredients. These products differ considerably in composition and are not interchangeable.
Check the exact plant species, plant part, extract type, amount and manufacturer directions before choosing.
How to choose a supplement from this category
- Identify the specific ingredient you are looking for: cranberry, D-mannose, Chanca Piedra or a botanical combination formula.
- Compare active ingredient amounts per serving.
- Check whether the same plants or minerals are already present in other supplements you use.
- If you take diuretics, blood pressure medicines, lithium or other prescription medicines, discuss compatibility with a healthcare professional first.
- If you have infection symptoms or suspect kidney stones, seek medical assessment first.
Frequently asked questions
What is Chanca Piedra used for?
Chanca Piedra is a botanical ingredient with a long history of traditional use in South America and is often associated with the urinary system. It should not be used as a substitute for medical treatment when kidney stones have been diagnosed.
What is Fo-Ti?
Fo-Ti is a plant used in traditional Chinese practice. Because liver injury has been reported with Polygonum multiflorum products, manufacturer directions and contraindications should be followed carefully.
Can cranberry be used when symptoms of a urinary tract infection appear?
Cranberry is widely used in supplements in this category, but pain, burning, frequent urination, fever or other symptoms of infection require medical assessment. Supplements do not replace diagnosis or treatment.
Can botanical diuretics be taken with blood pressure medicines?
Botanical diuretic formulas may affect fluid and electrolyte balance and can potentially interact with some medicines. If you take blood pressure medicines, diuretics, lithium or other prescription medicines, discuss the combination with a doctor or pharmacist.
This information is for general reference and is not medical advice. It does not replace consultation with a doctor, particularly in cases of infection symptoms, suspected kidney stones or regular prescription medicine use.